-
Tool Development
Unraveling Life's “Here and Now” Activity with Nucleic Acid Sensors
We are developing technology that utilizes nucleic acids with molecular recognition capabilities, such as aptamers and riboswitches, to detect the “where” and "when" of specific molecules in vivo in real-time. This enables the visualization of biological phenomena that were previously difficult to observe "as they happen," providing new analytical methods to get closer to the essence of dynamic biological processes.
-
Pharmaceutical development
The potential of new drugs brought about by RNA hacking
RNA hacking, which we developed, is an innovative technology that artificially alters the three-dimensional structure of target mRNA to control protein translation. This mechanism can form the basis of next-generation therapies that overcome the challenges faced by existing nucleic acid drugs. By selectively controlling the function of target genes while suppressing side effects, this technology is expected to offer a new approach to diseases that have been difficult to treat.
Student days
This is how we think.
The Ihara Laboratory / Katsuta Group promotes chemical biology research centered on nucleic acids. What is "Chemical Biology"? “Chemical-initiated Biology,” in other words, unraveling life phenomena through the power of chemistry, It is an academic field that aims to control. Among these, we focus on nucleic acid molecules such as DNA and RNA, Developing novel molecular sensors using artificially designed and synthesized nucleic acids, and We are challenging drug discovery applications that have mastered life control. For example, nucleic acid-based in vivo sensors that capture changes in RNA structure within cells, or RNA hacking, which precisely controls RNA translation, and other methods We are conducting innovative research that manipulates life phenomena at the molecular level. Our laboratory fuses diverse approaches across the boundaries of chemistry, biology, and biomedical engineering. We aim to contribute to next-generation life sciences and medicine. We welcome students and postdoctoral researchers with a spirit of inquiry and a drive to challenge themselves!
This is what we do.
This is who we are!
This page introduces a list of our currently active student members, the technical staff who support them, and members who have gone on to various paths after graduation, along with their post-graduation employment destinations.
The Katsuta Group welcomes motivated individuals! If you are interested in research, please feel free to contact us!
Contact
Contact us here
National University Corporation
Graduate School of Science and Technology, Kumamoto University
Ihara Laboratory, Katsuta Group
ACCESS
Location
860-8555
2-39-1 Kurokami, Chuo Ward, Kumamoto City, Kumamoto Prefecture